Pregnancy outcomes in pregnant women taking oral probiotic undergoing cerclage compared to placebo: two blinded randomized controlled trial

Autor: Raziyeh Vanda, Tahora Dastani, Seyed-Abdolvahab Taghavi, Hossein Sadeghi, Nicky Lambert, Fatemeh Bazarganipour
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-8 (2024)
Druh dokumentu: article
ISSN: 1471-2393
DOI: 10.1186/s12884-024-06496-x
Popis: Abstract Aim The purpose of this study is to evaluate the oral probiotic effect on pregnancy outcomes in pregnant women undergoing cerclage compared to placebo. Methods This study was a double-blind randomized clinical trial undertaken in Yasuj, Iran. 114 eligible participants who have undergone cerclage were randomly divided to either receive probiotic adjuvant or 17α-OHP (250 mg, IM) with placebo from the 16th -37th week of pregnancy by “block” randomization method. Our primary outcomes were preterm labor (PTB) (late and early) and secondary outcomes were other obstetrical and neonatal outcomes included preterm pre-labor rupture of membranes (PPROM), pre-labor rupture of membranes (PROM), mode of delivery, and neonatal outcomes including anthropometric characterize and Apgar score (one and fifth-minute). Results Results show that there are no statistically significant differences between the two groups in terms of PTB in
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje