Millisecond dynamics of an unlabeled amino acid transporter

Autor: Tina R. Matin, George R. Heath, Gerard H. M. Huysmans, Olga Boudker, Simon Scheuring
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-18811-z
Popis: Excitatory amino acid transporters (EAATs) are crucial for the removal of excitatory amino acids from the synaptic cleft. Here authors combined high-speed atomic force microscopy line-scanning with automated state assignment for the determination of transport dynamics of GltPh, a prokaryotic EAAT homologue, with millisecond temporal resolution.
Databáze: Directory of Open Access Journals