Re-biopsy of partially sampled thin melanoma impacts sentinel lymph node sampling as well as surgical margins
| Autor: | Evan S Weitman, Matthew C Perez, Daniel Lee, Youngchul Kim, William Fulp, Vernon K Sondak, Amod A Sarnaik, Ricardo J Gonzalez, Carl W Cruse, Jane L Messina, Jonathan S Zager |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Melanoma Management, Vol 6, Iss 2 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2045-0893 2045-0885 |
| DOI: | 10.2217/mmt-2018-0011 |
| Popis: | Aim: To assess the impact of re-biopsy on partially sampled melanoma in situ (MIS), atypical melanocytic proliferation (AMP) and thin invasive melanoma. Materials & methods: We retrospectively identified cases of re-biopsied partially sampled neoplasms initially diagnosed as melanoma in situ, AMP or thin melanoma (Breslow depth ≤0.75 mm). Results & conclusion: Re-biopsy led to sentinel lymph node biopsy (SLNB) in 18.3% of cases. No patients upstaged from AMP or MIS had a positive SLNB. One out of nine (11.1%) initially diagnosed as a thin melanoma ≤0.75 mm, upstaged with a re-biopsy, had a positive SLNB. After re-biopsy 8.5% underwent an increased surgical margin. Selective re-biopsy of partially sampled melanoma with gross residual disease can increase the accuracy of microstaging and optimize treatment regarding surgical margins and SLNB. |
| Databáze: | Directory of Open Access Journals |
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