Cognitive profile of children with sickle cell anemia compared to healthy controls

Autor: Isabel Pimenta Spínola Castro, Marcos Borato Viana
Jazyk: portugalština
Rok vydání: 2019
Předmět:
Zdroj: Jornal de Pediatria (Versão em Português), Vol 95, Iss 4, Pp 451-457 (2019)
Druh dokumentu: article
ISSN: 2255-5536
DOI: 10.1016/j.jpedp.2018.08.005
Popis: Objective: To evaluate the cognitive abilities of children and adolescents with sickle cell anemia diagnosed through neonatal screening and to compare them with healthy controls, adjusting the results to their socioeconomic status. Methods: Cognitive assessment was performed with the Wechsler WISC‐III scale in 64 children and adolescents with sickle cell anemia and in 64 controls matched by gender and age, without the disease and without neurological impairment; socioeconomic status was measured by the Criterion Brasil. Results: All cognitive scores were lower in the group of patients. The mean overall IQ, Verbal IQ, and Performance IQ were, respectively, 90.95 for the group of patients and 113.97 for the controls (p
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