| Autor: |
Luís Jesuíno de Oliveira Andrade, Larissa Santos França, Paulo Roberto Santana de Melo, Marcelo Araújo |
| Jazyk: |
English<br />Portuguese |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Jornal Vascular Brasileiro, Vol 13, Iss 3, Pp 192-197 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1677-7301 |
| DOI: |
10.1590/jvb.2014.025 |
| Popis: |
Prescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descriptive bibliographical review based on the results of a search of the Medline international database. The criteria for review were publication between January 1985 and November 2013, and the MeSH (Medical Subject Heading) keywords "off-label use" OR "off-label" OR "off-label prescribing" plus "diabetic foot" were input on the search form. Nine studies were selected that contained information about off-label treatments for the diabetic foot. We conclude that the practice of off-label prescribing has potential benefits. In some situations an off-label prescription is the only treatment available for patients, either because a more targeted drug does not exist, or because other methods of treatment are ineffective or unavailable due to patient intolerance. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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