THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUID

Autor: V I Shishkin, G. V. Kudriavtzeva, A B Ryabkov
Jazyk: ruština
Rok vydání: 2001
Předmět:
Zdroj: Научно-практическая ревматология, Vol 39, Iss 5, Pp 34-38 (2001)
Druh dokumentu: article
ISSN: 1995-4484
1995-4492
DOI: 10.14412/1995-4484-2001-469
Popis: Clinical and laboratory study was carried out including 30 pts with definite diagnosis of osteoarthritis (OA ) of knee joint. The effect of chondroitin sulfate (Structum) on basic bio-energetic indices of synovial fluid was studied. The obtained results testify to the fact that the expressed local hypoxia of cartilage tissue favoring the development, conserving and chronization of inflammatory process in synovial environment of knee joint in О A is successfully arrested by the above drug. Simultaneously bio-energetic parameters of synovial fluid were normalized: the level of oxygen absorption by synovial cells, the activity of a number of enzymes of hydrogen-phosphor (energetic) metabolism as well as of glucuronidaze and gialuronidaze,
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