Inflammation-related adverse reactions following vaccination potentially indicate a stronger immune response
| Autor: | Chun-Lan Zhuang, Zhi-Jie Lin, Zhao-Feng Bi, Ling-Xian Qiu, Fang-Fang Hu, Xiao-Hui Liu, Bi-Zhen Lin, Ying-Ying Su, Hui-Rong Pan, Tian-Ying Zhang, Shou-Jie Huang, Yue-Mei Hu, You-Lin Qiao, Feng-Cai Zhu, Ting Wu, Jun Zhang, Ning-Shao Xia |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Emerging Microbes and Infections, Vol 10, Iss 1, Pp 365-375 (2021) |
| Druh dokumentu: | article |
| ISSN: | 22221751 2222-1751 |
| DOI: | 10.1080/22221751.2021.1891002 |
| Popis: | Concerns about vaccine safety are an important reason for vaccine hesitancy, however, limited information is available on whether common adverse reactions following vaccination affect the immune response. Data from three clinical trials of recombinant vaccines were used in this post hoc analysis to assess the correlation between inflammation-related solicited adverse reactions (ISARs, including local pain, redness, swelling or induration and systematic fever) and immune responses after vaccination. In the phase III trial of the bivalent HPV-16/18 vaccine (Cecolin®), the geometric mean concentrations (GMCs) for IgG anti-HPV-16 and -18 (P |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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