Intra-arterial lidocaine administration during uterine fibroid embolization to reduce the immediate postoperative pain: a prospective randomized study

Autor: Stevo Duvnjak, Poul Erik Andersen
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: CVIR Endovascular, Vol 3, Iss 1, Pp 1-5 (2020)
Druh dokumentu: article
ISSN: 2520-8934
DOI: 10.1186/s42155-020-0099-4
Popis: Abstract Background To investigate if intra-arterial lidocaine administrated immediately after the embolisation endpoint reduces the pain. Methods Forty patients were randomised and 36 completed the study for purposes of analysis. In one group, the patients got 1% 10 ml lidocaine (100 mg) administered into each uterine artery immediately after embolisation with microspheres. The other group was embolised without supplementary lidocaine. The patients scored their pain on a visual analogue scale (VAS) 2 h, 4 h, 7 h, 10 h and 24 h after embolisation, and the total amount of used morphine was noted. Three-month follow-up MRI control was scheduled for all the patients to investigate the infarction rate. Results Embolisation was performed without any complications and with embolisation of both uterine arteries in all cases. Intra-arterial lidocaine was administered in all 20 patients without complications, and 20 patients in a control group did not receive lidocaine intra-arterial. VAS schemes showed a significant reduction in pain experience 2 h after UFE where mean pain score in the lidocaine group was 42.7 ± 21.4 compared with the control group in which the mean pain score was 61.1 ± 20.4 (p
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