Multisite evaluation of point of care CD4 testing in Papua New Guinea.

Autor: Malin Malagun, Gideon Nano, Caroline Chevallier, Ragagalo Opina, Gola Sawiya, Joseph Kivavia, Albina Kalinoe, Kathalina Nathaniel, Oscillah Kaminiel, John Millan, Andrea Carmone, Mary Dini, Theresa Palou, Kum Topma, Evelyn Lavu, Jessica Markby
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: PLoS ONE, Vol 9, Iss 11, p e112173 (2014)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0112173
Popis: Laboratory-based CD4 monitoring of HIV patients presents challenges in resource limited settings (RLS) including frequent machine breakdown, poor engineering support and limited cold chain and specimen transport logistics. This study assessed the performance of two CD4 tests designed for use in RLS; the Dynal assay and the Alere PIMA test (PIMA). Accuracy of Dynal and PIMA using venous blood was assessed in a centralised laboratory by comparison to BD FACSCount (BD FACS). Dynal had a mean bias of -50.35 cells/µl (r(2) = 0.973, p
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