Delayed Hypersensitivity Reaction to Titanium-coated Polypropylene Mesh in Breast Reconstruction

Autor: Eva Jouve, MD, Françoise Giordano-Labadie, MD, Gabrielle Selmes, MD, Marc Soule-Tholy, MD, Anne-Sophie Navarro, MD, Dimitri Gangloff, MD, Thomas Meresse, MD, Raphaelle Duprez-Paumier, MD, Emilie Tournier, MD, Charlotte Vaysse, PhD, MD
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Plastic and Reconstructive Surgery, Global Open, Vol 10, Iss 4, p e4232 (2022)
Druh dokumentu: article
ISSN: 2169-7574
00000000
DOI: 10.1097/GOX.0000000000004232
Popis: Summary:. Breast implant reconstructions increasingly incorporate meshes like the synthetic nonresorbable titanium-coated polypropylene mesh commercialized as Tiloop (Pfm medical). We report the case of a 48-year-old woman, with a medical history of nickel allergy, who presented with an extensive erythematous eruption, a periprosthetic reaction, and an axillary node reaction, 18 months after a unilateral prophylactic mastectomy. We excluded infectious, sarcoidosis and carcinomatosis. The patient’s medical history, the clinical evolution, and the particularly fast and complete healing after removal of the mesh were suggestive of an unusual allergic reaction to the titanium in the titanium-coated polypropylene mesh. Titanium allergies are very rare events, predominantly described in the dental and orthopedic fields. We also discussed the hypothesis of a tardive red breast syndrome related to a synthetic mesh, also mediated by immunological response as described recently in another case report.
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