| Autor: |
Zhenshan Zhu, Yaping Ju, Chuhua Zhang |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Applied Sciences, Vol 10, Iss 22, p 7979 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2076-3417 |
| DOI: |
10.3390/app10227979 |
| Popis: |
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a highly prevalent respiratory disorder. The knowledge of respiratory flow is an essential prerequisite for the establishment and development of OSAHS physiology, pathology, and clinical medicine. We made the first in-vitro experimental attempt to measure the oscillatory flow velocity in a computed tomography (CT) scanned extra-thoracic airway (ETA) model with OSAHS by using the particle image velocimetry (PIV) technique. In order to mimic respiration flow, three techniques were adopted to address difficulties in in-vitro experimental modeling: (1) fabricating the obstructive ETA measurement section with the CT-scanned data of an OSAHS patient airway; (2) maintaining the measurement accuracy by using the optical index-matching technique; (3) reproducing the oscillatory respiratory flow rates with the compiled clinical data of transient tidal volumes. The in-vitro measurements of oscillatory respiratory flow velocity manifested the time evolution of the complex OSAHS flow patterns, and the potential wall collapse of the ETA model with OSAHS. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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