Comparison of efficacy and safety of different suction pressure for speeding non-ventilated lung collapse in uniport video-assisted thoracoscopic surgery: a randomized-controlled trial

Autor: Yulin Li, Haihui Huang, Lihua Hang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Surgery, Vol 24, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 1471-2482
DOI: 10.1186/s12893-024-02539-4
Popis: Abstract Background The bronchial suction has been applied in speeding lung collapse. Low suction pressure may not speed lung collapse, but high pressure causes occult lung injury. The aim of the study was to explore efficacy and safety of different suction pressure for speeding lung collapse. Methods Eighty-four subjects undergoing uniport video-assisted thoracoscopic surgery (VATS) were randomly assigned for non-suction (Group 0), -10 cmH2O suction pressure (Group − 10), and − 30 cmH2O suction pressure (Group − 30). The primary outcome were the lung collapse scores (LCS) at 0 min (T0) after the visualization of the lung using a 10-point visual analogue scale and area under the curve (AUC) of LCS over time. The secondary outcomes included disconnection from the ventilator, the assessment of occult lung injury using NOS-3 expression, histologic scores of lung injury, and lung W/D weight ratio, intraoperative hypoxemia, the incidence of perioperative pulmonary complications. Results Both the LCS at T0 and AUC analysis showed that compared with Group 0, Group − 10 and Group − 30 significantly achieved good lung collapse (P
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