Estimation of healthcare‐related charges in women with BRCA mutations and breast cancer

Autor: Joseph Biskupiak, Sudhir Unni, Claire Telford, Minkyoung Yoo, Xiangyang Ye, Rishi Deka, Diana Brixner, David Stenehjem
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Health Services Research, Vol 21, Iss 1, Pp 1-10 (2021)
Druh dokumentu: article
ISSN: 1472-6963
DOI: 10.1186/s12913-020-06038-z
Popis: Abstract Background Breast cancer costs were estimated at $16.5 billion in 2010 and were higher than other cancer costs. There are limited studies on breast cancer charges and costs by BRCA mutations and receptor status. We examined overall health care and breast cancer-related charges by BRCA status (BRCAm vs. BRCAwt), receptor status (HER2+ vs. HER2-), and treatment setting (neoadjuvant vs. adjuvant). Methods Retrospective cohort study of charge data from 1995-2014 in an academic medical center. Facilities, physician, pharmacy, and diagnosis-related charges were presented as mean and median charges with standard deviation (SD) and interquartile ranges (25%-75%). Wilcoxon rank-sum test was used to assess statistically significant differences in charges between comparators. Results Total median breast-cancer related charges were $65,414 for BRCAm and $54,635 for BRCAwt (p=0.19); however all-cause charges were higher for BRCAm patients ($145,066 vs. $119,119, p
Databáze: Directory of Open Access Journals
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