A naturalistic study of plasma lipid alterations in female patients with anorexia nervosa before and after weight restoration treatment

Autor: Alia Arif Hussain, Jessica Carlsson, Erik Lykke Mortensen, Simone Daugaard Hemmingsen, Cynthia M. Bulik, René Klinkby Støving, Jan Magnus Sjögren
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Eating Disorders, Vol 12, Iss 1, Pp 1-14 (2024)
Druh dokumentu: article
ISSN: 2050-2974
DOI: 10.1186/s40337-024-01055-3
Popis: Abstract Background Plasma lipid concentrations in patients with anorexia nervosa (AN) seem to be altered. Methods We conducted a naturalistic study with 75 adult female patients with AN and 26 healthy female controls (HC). We measured plasma lipid profile, sex hormones and used self-report questionnaires at admission and discharge. Results Total cholesterol (median (IQR): 4.9 (1.2)) and triglycerides (TG) (1.2 (0.8)) were elevated in AN at admission (BMI 15.3 (3.4)) compared with HC (4.3 (0.7), p = 0.003 and 0.9 (0.3), p = 0.006) and remained elevated at discharge (BMI 18.9 (2.9)) after weight restoration treatment. Estradiol (0.05 (0.1)) and testosterone (0.5 (0.7)) were lower in AN compared with HC (0.3 (0.3), p =
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