| Popis: |
Background: Summer savory- Satureja hortensis L. is from Lamiaceae family and has antioxidant, anti-inflammatory, anti-apoptotic properties. The purpose of this study is to investigate the effect of hydro-alcoholic extract of Summer Savory leaves on the level of LH, FSH and testosterone in male rats exposed to chronic immobilization stress. Material and Methods: This study was conducted experimentally. 48 adult male Wistar rats were divided into 6 groups including: Control, Stress, Savory 200, Savory 400, Stress-Savory 200, and Stress-Savory 400. Groups 2, 5, and 6 were placed into restrainer for 6hours per day during 21 consecutive days and groups 3, 4, 5, and 6 were gavaged by hydro-alcoholic extract of Summer Savory with different doses of 200,400mg/kg during 21consecutive days. The level of LH, FSH and testosterone were measured by the end of period. Results: Chronic Immobilization caused significant decrease in serum concentrations of LH (p |
