Evaluation and Comparison of MRI Findings in Children with Global Developmental Delay and Isolated Neurodevelopmental Delay: A Cross-sectional Study

Autor: Nahideh Khosroshahi, Morteza Danaeian, Alireza Tavasoli, seyed Mehdi Alehossein, Kamyar Kamrani, Ayda Khabazi Oskuoei
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Clinical and Basic Research, Vol 5, Iss 3, Pp 52-59 (2021)
Druh dokumentu: article
ISSN: 2538-3736
Popis: Background and objectives: Neuro-developmental delay (NDD) is a chronic neurologic problem that adversely affects the quality of life of affected individuated. The aim of this study was to compare magnetic resonance imaging (MRI) findings in patients with global developmental delay (GDD) and Isolated NDD and evaluate their efficacy in diagnostic approach to children with NDD. Methods: A cross-sectional study was designed to enroll all patients with static developmental delay who had been referred to outpatient neurology clinic at Bahrami hospital, Tehran, Iran, between Feb 2012-Feb 2013. Neurologic examination results and the presence of GDD or Isolated NDD in patients were recorded using of a pre-prepared questionnaire, Bayley Scales for Infants and Toddler-4th edition and Denver Developmental Screening Test. Results: Totally 140 patients with developmental delay were enrolled during the study. 70 patients (50%) had global developmental delay (GDD), and 70 cases (50%) had Isolated NDD. In addition, abnormal associated neurological symptoms were present in 67.9% of patients. Patients whit GDD had significantly probability of abnormal MRI compare to patients with isolated NDD (P
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