Preoperative high-intensity training in frail old patients undergoing pulmonary resection for NSCLC

Autor: Salvi Rosario, Meoli Ilernando, Cennamo Antonio, Perrotta Fabio, Saverio Cerqua Francesco, Montesano Raffaele, Curcio Carlo, Lassandro Francesco, Stefanelli Francesco, Grella Edoardo, Tafuri Domenico, Mazzarella Gennaro, Bianco Andrea
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Open Medicine, Vol 11, Iss 1, Pp 443-448 (2016)
Druh dokumentu: article
ISSN: 2391-5463
DOI: 10.1515/med-2016-0079
Popis: Thoracic surgery remains the better therapeutic option for non-small cell lung cancer patients that are diagnosed in early stage disease. Preoperative lung function assessment includes respiratory function tests (RFT) and cardio-pulmonary exercise testing (CPET). Vo2 peak, FEV1 and DLCO as well as recognition of performance status, presence of co-morbidities, frailty indexes, and age predict the potential impact of surgical resection on patient health status and survival risk. In this study we have retrospectively assessed the benefit of a high-intensity preoperative pulmonary rehabilitation program (PRP) in 14 patients with underlying lung function impairment prior to surgery. Amongst these, three patients candidate to surgical resection exhibited severe functional impairment associated with high score of frailty according CHS and SOF index, resulting in a substantial mortality risk.
Databáze: Directory of Open Access Journals