Exposure to potentially inappropriate medications in Brazilian elderly outpatients with metabolic diseases

Autor: Vanessa dos Santos Martins, Ana Luiza Pereira Moreira Mori, Egidio Lima Dorea, Gelba Almeida Pinto, Mario Hiroyuki Hirata, Felipe Dominguez Crespo Hirata, Rosario Dominguez Crespo Hirata
Jazyk: angličtina
Předmět:
Zdroj: Brazilian Journal of Pharmaceutical Sciences, Vol 52, Iss 4, Pp 699-707
Druh dokumentu: article
ISSN: 2175-9790
1984-8250
DOI: 10.1590/s1984-82502016000400014
Popis: ABSTRACT Management of pharmacotherapy in elderly with metabolic diseases is challenging and potentially inappropriate medications (PIMs) are risk factors for drug interactions and adverse events. The exposure to PIMs in elderly outpatients with metabolic diseases and its relationship with polypharmacy and other variables was investigated. PIMs prescribed to 207 elderly patients (aged 60 to 96 years) with metabolic diseases who attended a University Hospital of Sao Paulo city, Brazil, from April/2010 to January/2011, were evaluated. PIMs were detected using both 2003 Beers and 2008 STOPP criteria. The association between PIMs and age, gender and polypharmacy was also examined. 2008 STOPP criteria detected more PIMs (44.4 %) than 2003 Beers criteria (16.0%, p
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