Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients

Autor:	Jennifer Clarke, Pierce Geoghegan, Natalie McEvoy, Maria Boylan, Orna Ní Choileáin, Martin Mulligan, Grace Hogan, Aoife Keogh, Oliver J. McElvaney, Oisín F. McElvaney, John Bourke, Bairbre McNicholas, John G. Laffey, Noel G. McElvaney, Gerard F. Curley
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Respiratory distress syndrome Adult Prone position Severe acute respiratory syndrome coronavirus 2 Medicine Biology (General) QH301-705.5 Science (General) Q1-390
Zdroj:	BMC Research Notes, Vol 14, Iss 1, Pp 1-6 (2021)
Druh dokumentu:	article
ISSN:	1756-0500
DOI:	10.1186/s13104-020-05426-2
Popis:	Abstract Objective We aimed to characterize the effects of prone positioning on respiratory mechanics and oxygenation in invasively ventilated patients with SARS-CoV-2 ARDS. Results This was a prospective cohort study in the Intensive Care Unit (ICU) of a tertiary referral centre. We included 20 consecutive, invasively ventilated patients with laboratory confirmed SARS-CoV-2 related ARDS who underwent prone positioning in ICU as part of their management. The main outcome was the effect of prone positioning on gas exchange and respiratory mechanics. There was a median improvement in the PaO2/FiO2 ratio of 132 in the prone position compared to the supine position (IQR 67–228). We observed lower PaO2/FiO2 ratios in those with low ( median) static compliance (P
Databáze:	Directory of Open Access Journals
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