Association of time‐restricted feeding, arterial age, and arterial stiffness in adults with metabolic syndrome

Autor: Maryam Alinezhad‐Namaghi, Saeid Eslami, Mohsen Nematy, Reza Rezvani, Adeleh Khoshnasab, Shokoofeh Bonakdaran, Elena Philippou, Abdolreza Norouzy
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Health Science Reports, Vol 6, Iss 7, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2398-8835
DOI: 10.1002/hsr2.1385
Popis: Abstract Background Time‐restricted feeding (TRF) is a kind of intermittent fasting defined as eating and drinking only during a certain number of hours in a day. It has been suggested that intermittent fasting may improve cardiovascular risk factors. This study evaluated the association of TRF and arterial stiffness, using pulse wave velocity (PWV), pulse wave analysis, and arterial age in metabolic syndrome participants. Methods A cohort study was carried out among metabolic syndrome adults who were followed over the Ramadan fasting period (used as a model of TRF since food was only allowed for about 8 h/day). The subjects were divided into Ramadan fasting and Ramadan nonfasting groups. The aortic PWV and central aortic pressure waveform were measured. Central systolic pressure, central pulse pressure, and indices of arterial compliance, such as augmentation pressure and augmentation index (AIx), were determined from waveform analysis. Results Ninety‐five adults (31.57% female, age: 45.46 ± 9.10 years) with metabolic syndrome (based on the International Diabetes Federation definition) participated in this study. Ramadan fasting and Ramadan nonfasting groups were including 80 and 15 individuals respectively. A significant reduction was seen in PWV (0.29 m/s), central systolic pressure (4.03 mmHg), central pulse pressure (2.43 mmHg), central augmentation pressure (1.88 mmHg), and central AIx (2.47) in the Ramadan fasting group (p = 0.014, p
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