Use of antihistamines before or during pregnancy and risk of early-onset pre-eclampsia in allergic women: a population-based cohort study

Autor: Nils-Halvdan Morken, Kim Christian Danielsson, Ingvild Dalen, Ragnar Kvie Sande, Anne K Sande, Erik Andreas Torkildsen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMJ Open, Vol 12, Iss 10 (2022)
Druh dokumentu: article
ISSN: 2022-0618
2044-6055
DOI: 10.1136/bmjopen-2022-061837
Popis: Objective We have previously found that allergy is a risk factor for early-onset pre-eclampsia. The aim of this study was to assess the association between pregestational maternal use of antihistamines and early-onset pre-eclampsia.Design A population-based cohort study.Setting and participants All women giving birth in Norway 2004–2016, including 692 487 pregnancies. Data from the Medical Birth Registry of Norway were linked with data from the Norwegian Prescription Database. Prescriptions of antihistamines were divided into three groups: before pregnancy (
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