Does the Daily Dose of Tadalafil for the Treatment of Erectile Dysfunction Increase Penile Sensation?

Autor: Selim Taş, Ekrem İslamoğlu, Ali Eren, Murat Savaş
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Urological Surgery, Vol 10, Iss 1, Pp 43-48 (2023)
Druh dokumentu: article
ISSN: 2148-9580
DOI: 10.4274/jus.galenos.2022.2022.0042
Popis: Objective:To investigate the effect of tadalafil, used for treating erectile dysfunction (ED) at a daily dose of 5 mg for 12 weeks, on penile sensation.Materials and Methods:Our study included 30 male patients who applied to our andrology outpatient clinic with the complaint of ED and were prescribed tadalafil at a daily dose of 5 mg for 12 weeks. Before treatment, serum levels of testosterone and luteinizing hormone (LH) were measured. Demographic and clinical characteristics were recorded. Pre- and post-treatment electromyography (EMG) examinations for penile sensation and International Index of Erectile Function (IIEF-5) scoring were performed for each patient.Results:The mean age was 53±9 years. The mean body mass index was 27±2. Before treatment, serum levels of testosterone and LH were within the normal range. There were 8 (29%) patients with diabetes mellitus and 7 (25%) patients with hypertension. The pre- and post-treatment IIEF-5 scores were 13±3 and 19±3, respectively. Nerve conduction velocities (NCV) increased from 35.5 m/sec to 38.05 m/sec. Latency values decreased from 2.32 ms to 2.14 ms. There was a statistically significant improvement in IIEF-5 scores and EMG results for penile sensation after treatment (IIEF-5, NCV and latency; p
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