| Autor: |
Edlaine Ferreira, Jefferson Lima, Renata Pereira Alves-Balvedi, Paulo Rogério Bonan, Eliton Medeiros, Luiz Goulart, Antonio Lima, Helmut Neff, Leiva Oliveira, Lucio Castellano, Artur Araújo, Cleumar Moreira |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Proceedings, Vol 1, Iss 4, p 536 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2504-3900 |
| DOI: |
10.3390/proceedings1040536 |
| Popis: |
The detection of Leishmania spp. through a disposable surface plasmon resonance (SPR) biochip, using mono- and polychromatic sources, is presented here. A highly specific and sensitive-constrained synthetic peptide (LC2) derived from a mimotope of Leishmania chagasi antigen was immobilized on the sensing region using a simple protocol. ELISA- and PCR-confirmed negative and positive sera of Leishmania chagasi infected patients were used. Detection of positive IgG showed a fast response with good sensitivity and specificity for the proposed method. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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