Comparison between Adventitial and Intimal Inflammation of Ruptured and Nonruptured Atherosclerotic Plaques in Human Coronary Arteries
| Autor: | Maria L. Higuchi, Paulo S. Gutierrez, Hiram G. Bezerra, Suely A. Palomino, Vera D. Aiello, Júlia M. L. Silvestre, Peter Libby, José A. F. Ramires |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2002 |
| Předmět: | |
| Zdroj: | Arquivos Brasileiros de Cardiologia, Vol 79, Iss 1, Pp 20-24 (2002) |
| Druh dokumentu: | article |
| ISSN: | 0066-782X 1678-4170 |
| DOI: | 10.1590/S0066-782X2002001000003 |
| Popis: | OBJECTIVE: To verify the possible role of adventitial inflammation in atherosclerotic plaque vulnerability and coronary artery remodelling. METHODS: We compared the mean numbers of lymphocytes in the adventitia and in the plaque of ruptured thrombosed and stable equi-stenotic coronary segments of 34 patients who died due to acute myocardial infarction. We also analysed adventitial microvessels, adventitial fibrosis and the external elastic membrane. RESULTS: In the adventitia, the numbers of lymphocytes and microvessels/mm² were 69.5±88.3 and 60.9± 32.1 in culprit lesions and 16.4 ± 21.1 and 44.3±16.1 in stable lesions (p |
| Databáze: | Directory of Open Access Journals |
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