Multistate Epidemiology of Histoplasmosis, United States, 2011–2014

Autor: Paige A. Armstrong, Brendan R. Jackson, Dirk Haselow, Virgie Fields, Malia Ireland, Connie Austin, Kimberly Signs, Veronica Fialkowski, Reema Patel, Peggy Ellis, Peter C. Iwen, Caitlin Pedati, Suzanne Gibbons-Burgener, Jannifer Anderson, Thomas Dobbs, Sherri Davidson, Mary McIntyre, Kimberly Warren, Joanne Midla, Nhiem Luong, Kaitlin Benedict
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 24, Iss 3, Pp 425-431 (2018)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid2403.171258
Popis: Histoplasmosis is one of the most common mycoses endemic to the United States, but it was reportable in only 10 states during 2016, when a national case definition was approved. To better characterize the epidemiologic features of histoplasmosis, we analyzed deidentified surveillance data for 2011–2014 from the following 12 states: Alabama, Arkansas, Delaware, Illinois, Indiana, Kentucky, Michigan, Minnesota, Mississippi, Nebraska, Pennsylvania, and Wisconsin. We examined epidemiologic and laboratory features and calculated state-specific annual and county-specific mean annual incidence rates. A total of 3,409 cases were reported. Median patient age was 49 (interquartile range 33–61) years, 2,079 (61%) patients were male, 1,273 (57%) patients were hospitalized, and 76 (7%) patients died. Incidence rates varied markedly between and within states. The high hospitalization rate suggests that histoplasmosis surveillance underestimates the true number of cases. Improved surveillance standardization and surveillance by additional states would provide more comprehensive knowledge of histoplasmosis in the United States.
Databáze: Directory of Open Access Journals