Prognostic significance of lymphocyte recovery in children with standard and high-risk precursor B acute lymphoblastic leukemia

Autor: Rahul Naithani, Muhammad Asim, Mohammad Abdelhaleem, Angela Punnett
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Pediatric Hematology Oncology Journal, Vol 4, Iss 2, Pp 51-55 (2019)
Druh dokumentu: article
ISSN: 2468-1245
DOI: 10.1016/j.phoj.2019.08.180
Popis: Background: The primary aim of this study was to determine if absolute lymphocyte count (ALC) at end of induction is an independent prognostic marker of event free survival (EFS) in children with precursor B-ALL. Material & Methods: This is a retrospective analysis of children (aged 1–18 years) diagnosed with standard and high-risk precursor B ALL. At day 29 of induction ALC (ALC29) ≥ 1.5 × 109/L was considered high and 1.5 × 109/L at day 29 of initial induction chemotherapy vs 40% for those with ALC
Databáze: Directory of Open Access Journals