Assessment of pulmonary functions in COVID-19 survivors and their clinical correlation at 6-month follow-up: A prospective observational study

Autor: Jimit Mistry, Ankita Kumari, Sunil Kumar, Manish Advani, Chandra Shekhar Purohit, Harsh Vyas
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Advanced Lung Health, Vol 3, Iss 3, Pp 97-102 (2023)
Druh dokumentu: article
ISSN: 2772-7165
2772-7173
DOI: 10.4103/jalh.jalh_13_23
Popis: Background: Long term impact of COVID-19 on pulmonary functions is still an area of active research. Objective: To assess pulmonary functions and their relationship with clinical severity of disease among COVID-19 survivors at six-month follow-up after being discharged from the hospital. Methods: It was a hospital based prospective observational six-month follow-up study. After fulfillment of all inclusion and exclusion criteria, subjects underwent spirometry and diffusion capacity of lung for carbon monoxide (DLco). Ninety-six subjects had completed the tests and were enrolled for the study. Categorization of subjects was made based on their clinical disease severity profile according to Government of India guidelines. Test results were correlated with clinical severity of disease. Results: Of 96 subjects, 46 were mild, 28 were moderate, 18 were severe and 4 were critical cases. Majority of subjects had normal spirometry (65.6 %) and DLco (66.6 %). Among abnormal lung functions, the commonest was reduced DLco (33.3%) followed by restrictive (18.7%), small airway disease (10.4 %), obstructive (3.1 %) and mixed (2%) spirometry patterns. With the advancement of clinical disease severity, the frequency of restrictive pattern (P
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