Understanding the Constraints and Optimization of Serum Immunofixation Electrophoresis and Serum Free Light Chains for Detecting Monoclonal Proteins: A Single-Center Experience

Autor:	Malvika Shastri, Pankaj Malhotra, Harvinder Kaur, Ritu Aggarwal
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	serum immunofixation serum free light chain multiple myeloma concordance discordance Medicine
Zdroj:	Journal of Laboratory Physicians, Vol 15, Iss 04, Pp 518-523 (2023)
Druh dokumentu:	article
ISSN:	0974-2727 0974-7826
DOI:	10.1055/s-0043-1768684
Popis:	Introduction Serum immunofixation electrophoresis (SIFE) and serum free light chain (SFLC) assay are imperative investigations in diagnosis and follow-up of multiple myeloma (MM). SFLC assays are reported to have higher sensitivity than SIFE. However, discrepancies have been reported between them. The current study was aimed at assessing concordance and discordance between SIFE and SFLC results in MM.
Databáze:	Directory of Open Access Journals
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