Recruitment strategies and consent rates in a national prospective colorectal cancer screening cohort: results from year 1 of the Voyage Study

Autor: Janet E Olson, Jennifer L St Sauver, Emily J Kirsch, Christine R Kirt, Bonny Kneedler, Jennifer J Laffin, Kathleen J Yost, Lila J Finney Rutten, Rachel E Carlson, Jessica A Grimm
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMJ Open Gastroenterology, Vol 11, Iss 1 (2024)
Druh dokumentu: article
ISSN: 2054-4774
DOI: 10.1136/bmjgast-2024-001376
Popis: Objective To identify the optimal incentive protocol for maximising participation while managing study costs during the Voyage trial.Design Prospective cohort (Voyage trial) of colorectal cancer (CRC) incidence and mortality outcomes in individuals screened with multitarget stool DNA (mt-sDNA) served as the population. A subset was randomised to receive postage stamps as a pre-consent incentive, or as a post-consent incentive after completion of the consent and questionnaire. Descriptive statistics from year 1 are reported.Results During year 1 of the Voyage trial, a total of 600 258 individuals with mt-sDNA orders received at Exact Sciences Laboratories were randomly selected and invited to participate. Of those, 26 429 (4.4%) opted in, 14 365 of whom (54.3%) consented. The opt-in and consent samples were similar to the target population with respect to sex but differed by geographic residence and age (p
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