Evaluation of vitamin D serum levels in asthmatic adults and their relationship with asthma control

Autor: Sandra Nora González-Diaz, Alfredo Arias-Cruz, Jesús Zacarías Villarreal-Pérez, Daniel Sánchez Guerra, Olga Patricia Monge-Ortega
Jazyk: English<br />Spanish; Castilian
Rok vydání: 2018
Předmět:
Zdroj: Revista Alergia México, Vol 65, Iss 4, Pp 362-371 (2018)
Druh dokumentu: article
ISSN: 0002-5151
2448-9190
DOI: 10.29262/ram.v65i4.386
Popis: Background: Decreased levels of vitamin D influence on the control and severity of asthma. Objective: To evaluate the relationship between vitamin D serum levels and asthma control, as well as nutritional status, quality of life and patient comorbidities. Methods: Cross-sectional, observational, descriptive study of 43 asthmatic patients older than 18 years of age. Multiple logistic and multiple linear regression multivariate analyses of variance were performed; a p-value ≤ 0.05 was considered to be statistically significant. Results: Insufficient vitamin D levels were determined in 83.7 % of patients; 93 % had at least one asthma exacerbation in the previous year. There was no relationship between vitamin D serum levels and asthma control as measured by ACT and FEV1. There was a significant association between body mass index and vitamin D levels (p = 0.013). With a quality of life questionnaire for asthmatic adults, 76.7 % were recorded to have a poor quality of life. Conclusions: No relationship was observed between vitamin D serum levels and asthma control in the patients. Most patients had insufficient vitamin D serum levels, uncontrolled asthma, and poor quality of life. Overweight and grade I obesity were associated with vitamin D insufficient levels.
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