Ketamine Therapy in Patients of Alcohol Use Disorder: A Prospective Pilot Study to Evaluate Abstinence Rate with This Add-on Treatment Modality
| Autor: | Nidhi Purushottum Marvania, Anto Leroy Rayan, Dhruti Vijaykumar Merchant, Drashti Paragkumar Shah, Prakash Ishwarlal Mehta, Fenil Dineshkumar Modh |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Annals of Indian Psychiatry, Vol 8, Iss 4, Pp 324-327 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2588-8358 2588-8366 |
| DOI: | 10.4103/aip.aip_110_24 |
| Popis: | Background: Alcohol use disorders (AUDs) are emerging as a substance use disorder having various psychological and physical ill effects leading to hampering of individual’s productivity and functioning. Aims: The aim of this study was to evaluate the efficacy of ketamine in enhancing confidence levels to abstain from alcohol. Methods: Eighteen patients were administered ketamine intravenously after detoxification; a total of three doses, with a 3-day gap between each. The Alcohol Abstinence Self-Efficacy Scale was used to measure their confidence in abstaining from alcohol. Results: The study revealed a significant increase in mean confidence scores after three ketamine sessions, with a final assessment showing a 51.98% increase in confidence from baseline. Conclusions: The study found that ketamine therapy significantly increased confidence levels in individuals with AUD to abstain from alcohol, with P = 0.05 threshold. However, the impact may wane over time, suggesting the need for additional support or maintenance treatments. |
| Databáze: | Directory of Open Access Journals |
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