Increase of invasive pneumococcal disease in children temporally associated with RSV outbreak in Quebec: a time-series analysisResearch in context

Autor: Naïm Ouldali, Geneviève Deceuninck, Brigitte Lefebvre, Rodica Gilca, Caroline Quach, Nicholas Brousseau, Bruce Tapiero, Philippe De Wals
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: The Lancet Regional Health. Americas, Vol 19, Iss , Pp 100448- (2023)
Druh dokumentu: article
ISSN: 2667-193X
DOI: 10.1016/j.lana.2023.100448
Popis: Summary: Background: Respiratory viruses have been previously suspected to trigger invasive pneumococcal disease (IPD). After progressive non-pharmaceutical interventions (NPI) lifting, an unusual RSV outbreak has been observed in the Fall 2021, raising concerns about the possible consequences on IPD. We aimed to analyse the evolution of IPD incidence across age-groups since NPI lifting, and its temporal association with respiratory viral infections. Methods: We conducted a time-series analysis using 1) population-based IPD surveillance data and 2) statistics from the laboratory surveillance network of respiratory viruses in the province of Quebec, Canada, from January 2013 to January 2022. The monthly IPD incidence was analysed by quasi-Poisson regression models across age-groups. The fraction of IPD incidence change potentially attributable to different viruses in 2021–2022 was estimated. Findings: A total of 7712 IPD cases were included. After a major decrease in IPD incidence from April 2020, IPD rate started to increase in
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