Neuroprotection and antioxidants

Autor: Maria Lalkovicová, Viera Danielisová
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Neural Regeneration Research, Vol 11, Iss 6, Pp 865-874 (2016)
Druh dokumentu: article
ISSN: 1673-5374
DOI: 10.4103/1673-5374.184447
Popis: Ischemia as a serious neurodegenerative disorder causes together with reperfusion injury many changes in nervous tissue. Most of the neuronal damage is caused by complex of biochemical reactions and substantial processes, such as protein agregation, reactions of free radicals, insufficient blood supply, glutamate excitotoxicity, and oxidative stress. The result of these processes can be apoptotic or necrotic cell death and it can lead to an irreversible damage. Therefore, neuroprotection and prevention of the neurodegeneration are highly important topics to study. There are several approaches to prevent the ischemic damage. Use of many modern therapeutical methods and the incorporation of several substances into the diet of patients is possible to stimulate the endogenous protective mechanisms and improve the life quality.
Databáze: Directory of Open Access Journals