NEW METHODS OF OPTIMIZATION OF EPILEPSY PHARMACOTHERAPY: USE OF BAYESIAN PHARMACOKINETIC MODELING

Autor: Z. А. Suslina, А. K. Sariev, D. А. Аbaimov, T. YU. Noskova, R. D. Sejfulla, V. V. Shvedkov, D. I. Prokhorov, M. V. Shiryaeva, L. А. Mota
Jazyk: ruština
Rok vydání: 2016
Předmět:
Zdroj: Эпилепсия и пароксизмальные состояния, Vol 4, Iss 2, Pp 40-47 (2016)
Druh dokumentu: article
ISSN: 2077-8333
2311-4088
Popis: There was carried out the therapeutic drug monitoring of antiepileptic drug carbamazepine by use of a bayesian mathematical modeling method in 47 patients with a focal epilepsy. The database of patients pharmacokinetic characteristics concerning carbamazepine was created. According the results of carbamazepine monitoring anticonvulsant dosage regimen was corrected
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