Gut health benefits of brown seaweed Ecklonia radiata and its polysaccharides demonstrated in vivo in a rat model

Autor: Suvimol Charoensiddhi, Michael A. Conlon, Pawadee Methacanon, Christopher M.M. Franco, Peng Su, Wei Zhang
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Journal of Functional Foods, Vol 37, Iss , Pp 676-684 (2017)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2017.08.040
Popis: We examined the gut health potential of the brown seaweed Ecklonia radiata and its polysaccharides. Rats consumed an AIN-93G-based diet without addition (control) or containing 5% (w/w) of ground dried whole seaweed (WS) or dried powdered polysaccharide fraction (PF) of the seaweed for 1 wk. The PF consisted largely of fucoidan and alginate. PF treatment increased cecal digesta weight relative to the control (1.36 ± 0.17 vs 0.60 ± 0.06 g/100 g body weight). Beneficial cecal total short chain fatty acids increased in response to WS (213.25 ± 14.40 μmol) and PF (208.59 ± 23.32 μmol) compared with the control (159.96 ± 13.10 μmol). Toxic protein fermentation product levels were decreased by WS and PF. Cecal numbers of bacteria relevant to gut health were determined using quantitative real-time PCR. Relative to the control, numbers of butyrate-producing Faecalibacterium prausnitzii were increased by PF supplementation, whereas WS decreased numbers of potentially pathogenic Enterococcus. In conclusion, E. radiata-derived polysaccharides have promise as prebiotic supplements.
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