Presence of secondary bladder cancer following radical nephroureterectomy for upper tract urothelial carcinoma: characteristics, risk factors, and predictive value

Autor: Shicong Lai, Pengjie Wu, Shengjie Liu, Samuel Seery, Jianyong Liu, Lei He, Ming Liu, Yaoguang Zhang, Jian-ye Wang, Tao Xu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Urology, Vol 22, Iss 1, Pp 1-8 (2022)
Druh dokumentu: article
ISSN: 1471-2490
DOI: 10.1186/s12894-022-01158-6
Popis: Abstract Background To assess the characteristics, predictive risk factors, and prognostic effect of secondary bladder cancer (SBCa) following radical nephroureterectomy (RNU) in upper tract urothelial carcinoma (UTUC). Methods Using the Surveillance, Epidemiology, and End Results database, the authors analyzed clinicopathologic characteristics and survival data from 472 UTUC patients with SBCa after RNU, between 2004 and 2017. Cox’s proportional hazard regression model was implemented to identify independent predictors associated with post-recurrence outcomes. The threshold for statistical significance was p
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