Spatial accuracy evaluation of magnetic source imaging methods on OPM-based MEG

Autor: Nan An, Fuzhi Cao, Wen Li, Wenli Wang, Weinan Xu, Chunhui Wang, Min Xiang, Yang Gao, Binbin Sui, Dawei Wang, Dexin Yu, Xiaolin Ning
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: iScience, Vol 25, Iss 10, Pp 105177- (2022)
Druh dokumentu: article
ISSN: 2589-0042
DOI: 10.1016/j.isci.2022.105177
Popis: Summary: The emergence of the optically pumped magnetometer (OPM)-based magnetoencephalography (MEG) has led to new developments in MEG technology. The source imaging results of different magnetic source imaging (MSI) methods show considerable differences, which makes it difficult for researchers to choose an appropriate method. This study assessed time-domain MSI methods implemented in the Brainstorm, FieldTrip, and SPM12 toolboxes using simulations. We proposed using a metric, variational free energy under the Bayesian framework, as an indicator to evaluate source imaging results because it does not require the ground truth of sources but uses the fitness of the measurement data. Our simulations demonstrated the effectiveness of the variational free energy in indicating the quality of the source reconstruction results. We then applied each MSI method to the real OPM-MEG experimental data. We aimed to highlight the characteristics of each method and provide references for researchers choosing an appropriate MSI method.
Databáze: Directory of Open Access Journals