Autor: |
Hans Gregersen, Yanmin Wang, Fred Field, Mengjun Wang, Kar Man Lo, Xiaomei Guo, William Combs, Ghassan S. Kassab |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Physiological Reports, Vol 10, Iss 11, Pp n/a-n/a (2022) |
Druh dokumentu: |
article |
ISSN: |
2051-817X |
DOI: |
10.14814/phy2.15338 |
Popis: |
Abstract Several technologies have been developed for assessing anorectal function including the act of defecation. We used a new prototype of the Fecobionics technology, a multi‐sensor simulated feces, to visualize defecatory patterns and introduced new metrics for anorectal physiology assessment in normal subjects. Fourteen subjects with normal fecal incontinence and constipation questionnaire scores were studied. The 10‐cm‐long Fecobionics device provided measurements of axial pressures, orientation, bending, and shape. The Fecobionics bag was distended to the urge‐to‐defecate level inside rectum where after the subjects were asked to evacuate. Physiological evacuation parameters were assessed. Special attention was paid to the Fecobionics rectoanal pressure gradient (F‐RAPG) during evacuation. Anorectal manometry (ARM) and balloon expulsion test (BET) were done as references. The user interface displayed the fine coordination between pressures, orientation, bending angle, and shape. The pressures showed that Fecobionics was expelled in 11.5 s (quartiles 7.5 and 18.8s), which was shorter than the subjectively reported expulsion time of the BET balloon. Six subjects did not expel the BET balloon within 2 min. The F‐RAPG was 101 (79–131) cmH2O, whereas the ARM‐RAPG was −28 (−5 to −47) cmH20 (p |
Databáze: |
Directory of Open Access Journals |
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