Depression and anxiety in a case series of amyotrophic lateral sclerosis: frequency and association with clinical features

Autor: Laura de Godoy Rousseff Prado, Isabella Carolina Santos Bicalho, Mauro Vidigal-Lopes, Vitor de Godoy Rousseff Prado, Rodrigo Santiago Gomez, Leonardo Cruz de Souza, Antônio Lúcio Teixeira
Jazyk: English<br />Portuguese
Předmět:
Zdroj: Einstein (São Paulo), Vol 15, Iss 1, Pp 58-60
Druh dokumentu: article
ISSN: 2317-6385
1679-4508
DOI: 10.1590/s1679-45082017ao3870
Popis: ABSTRACT Objective To investigate the frequency of anxiety and depression and their association with clinical features of amyotrophic lateral sclerosis. Methods This is a cross-sectional and descriptive study including a consecutive series of patients with sporadic amyotrophic lateral sclerosis according to Awaji’s criteria. Patients underwent clinical and psychiatric assessment (anxiety and depression symptoms). Results We included 76 patients. The men/women ratio was 1.6:1. Participants’ mean age at disease onset was 55 years (SD±12.1). Sixty-six patients (86.8%) were able to complete psychiatric evaluation. Clinically significant anxiety was found in 23 patients (34.8%) while clinically significant depression was found in 24 patients (36.4%). When we compared patients with and without depression a significant difference was seen only in the frequency of anxiety symptoms (p
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