Early prolonged prone position in noninvasively ventilated patients with SARS-CoV-2-related moderate-to-severe hypoxemic respiratory failure: clinical outcomes and mechanisms for treatment response in the PRO-NIV study

Autor:	Giovanni Musso, Claudio Taliano, Federica Molinaro, Caterina Fonti, Deliana Veliaj, Davide Torti, Elena Paschetta, Elisabetta Castagna, Giorgio Carbone, Luigi Laudari, Claudio Aseglio, Edoardo Zocca, Sonia Chioni, Laura Ceretto Giannone, Federica Arabia, Cecilia Deiana, Francesca Maria Benato, Marta Druetta, Giorgio Campagnola, Margherita Borsari, Martina Mucci, Tiziana Rubatto, Mara Peyronel, Gloria Tirabassi
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Noninvasive ventilation Ventilatory ratio Corrected minute ventilation Lung ultrasound Dead space Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Zdroj:	Critical Care, Vol 26, Iss 1, Pp 1-32 (2022)
Druh dokumentu:	article
ISSN:	1364-8535
DOI:	10.1186/s13054-022-03937-x
Popis:	Abstract Background Whether prone position (PP) improves clinical outcomes in COVID-19 pneumonia treated with noninvasive ventilation (NIV) is unknown. We evaluated the effect of early PP on 28-day NIV failure, intubation and death in noninvasively ventilated patients with moderate-to-severe acute hypoxemic respiratory failure due to COVID-19 pneumonia and explored physiological mechanisms underlying treatment response. Methods In this controlled non-randomized trial, 81 consecutive prospectively enrolled patients with COVID-19 pneumonia and moderate-to-severe (paO2/FiO2 ratio
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/a9375847766849748d69b91f6802ba79 Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ