| Autor: |
Xiangbin Xiao, Zhi Luo, Minjian Peng, Hui Yan, Dengliang Yi, Zigang Du, Ji Liu |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Heliyon, Vol 10, Iss 15, Pp e35201- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2405-8440 |
| DOI: |
10.1016/j.heliyon.2024.e35201 |
| Popis: |
Background: Cardioembolic stroke is a type of ischemic stroke with high disability and mortality, a high recurrence rate and poor prognosis. miRNAs have been explored as potential noninvasive biomarkers in atrial fibrillation and ischemic stroke, but their expression profile in cardioembolic stroke still needs to be explored. This study will explore the differences in miRNA expression between cardioembolic stroke patients and healthy people through meta-analysis and attempt to analyze the target genes by bioinformatics analysis. Methods: Literature databases and gene expression databases were searched from the inception date to June 2022. The study reported the circulating miRNA expression profiles in cardioembolic stroke patients and healthy controls. miRNAs with significantly differential expression and their target genes were analyzed. Results: Three articles and one gene expression dataset were included in the analysis. The results showed that miR-21–5p (SMD: 2.16; 95 % CI: 1.57, 2.75; p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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