Synthesis and mechanistic study of 2-(trifluoromethyl)-10H-phenoselenazine from double cross coupling reaction
| Autor: | CÁSSIO SIQUEIRA, GIANLUCA CIANCALEONI, SUMBAL SABA, ANTONIO L. BRAGA, JAMAL RAFIQUE, GIANCARLO V. BOTTESELLE |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Anais da Academia Brasileira de Ciências, Vol 96, Iss 1 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1678-2690 0001-3765 |
| DOI: | 10.1590/0001-3765202420230745 |
| Popis: | Abstract Phenoselenazines are nitrogen and selenium-based heterocyclic compounds that have important biological activities. However, their preparation methods are scarce and difficult to handle. The synthesis of a phenoselenazine from a simple and robust CuO nanoparticle catalyzed methodology, using bis-aniline-diselenide and 1,2-dihalobenzenes under microwave irradiation. Also, the double-cross-coupling reaction mechanism for C-Se and C-N bond formation, including the observation of a reaction intermediate by mass spectrometry have been studied. |
| Databáze: | Directory of Open Access Journals |
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