Photo-Induced, Phenylhydrazine-Promoted Transition-Metal-Free Dehalogenation of Aryl Fluorides, Chlorides, Bromides, and Iodides

Autor:	Yiwei Zhu, Zhimin Wu, Hongcai Sun, Junjun Ding
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	photo-induced hydrogenation radical-mediated hydrogenation aryl halides Organic chemistry QD241-441
Zdroj:	Molecules, Vol 28, Iss 19, p 6915 (2023)
Druh dokumentu:	article
ISSN:	1420-3049
DOI:	10.3390/molecules28196915
Popis:	In this study, we present a straightforward and highly effective photo-triggered hydrogenation method for aryl halides, devoid of transition-metal catalysts. Through the synergistic utilization of light, PhNHNH2, and a base, we have successfully initiated the desired radical-mediated hydrogenation process. Remarkably, utilizing mild reaction conditions, a wide range of aryl halides, including fluorides, chlorides, bromides, and iodides, can be selectively transformed into their corresponding (hetero)arene counterparts, with exceptional yields. Additionally, this approach demonstrates a remarkable compatibility with diverse functional groups and heterocyclic compounds, highlighting its versatility and potential for use in various chemical transformations.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/e936696bf7c841df8fce6e2807c6d6d8 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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