| Autor: |
Hao Wan, Xiangpeng Zhan, Xuwen Li, Tao Chen, Xinxi Deng, Yang Liu, Jun Deng, Bin Fu, Yu Li |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
BMC Urology, Vol 23, Iss 1, Pp 1-11 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2490 |
| DOI: |
10.1186/s12894-023-01342-2 |
| Popis: |
Abstract Purpose To investigate prognostic values of prostatic urethra involvement (PUI) and construct a prognostic model that estimates the probability of cancer-specific survival for T1 bladder cancer patients. Method and materials We investigated the national Surveillance, Epidemiology, and End Results (SEER) database (2004–2015) to get patients diagnosed with T1 bladder cancer. An external validation cohort was obtained from the First Affiliated Hospital of Nanchang University. The Kaplan–Meier method with the log-rank test was applied to assess cancer-specific survival (CSS) and overall survival (OS). Moreover, the propensity score matching (PSM) and multivariable Cox proportional hazard model were performed. All patients were randomly divided into the development cohort and validation group at the ratio of 7:3. The performance of the model was internally validated by calibration curves and the concordance index (C-index). Results The PUI group had a lower survival rate of both CSS and overall survival OS before and after PSM when compared to non-involved patients (All P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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