A Minimally Invasive Method for the Treatment of Post-Traumatic Disorders of the Bone Union of the Tibia
| Autor: | V. F. Lebedev, L. A. Dmitriyeva, I. A. Shuruguna, P. N. Khaziyev |
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| Jazyk: | ruština |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Acta Biomedica Scientifica, Vol 5, Iss 5, Pp 107-111 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2541-9420 2587-9596 |
| DOI: | 10.29413/ABS.2020-5.5.14 |
| Popis: | Background. The ability to control regeneration processes is a key link in the development of methods for treating patients with post-traumatic disorders of reparative osteogenesis. Aim of the study. To evaluate the effectiveness of the fusion of the tibia by local application of the interferon-beta preparation with autogenous bone marrow punctate in post-traumatic disorders of reparative regeneration.Material and methods. The analysis of the effectiveness of clinical application of autogenous bone marrow with interferon-beta-1b in 64 patients with delayed consolidation and pseudarthrosis of the tibia was carried out. All patients underwent external bone fixation. In order to optimize reparative osteogenesis during the operation, a mixture containing 3–4 ml of bone marrow with 8 million IU/0.5 ml of interferon beta-1b solution was injected locally into the interfragmental space.Results. With puncture local injection of interferon-beta with punctate of autogenous bone marrow with delayed consolidation, fusion of the tibial fracture was achieved in 100 % of cases. In patients with a diagnosis of a pseudarthrosis of the tibia, a positive result was achieved in 90.3 % of cases. Thus, the local application of autogenous bone marrow together with the interferon-beta preparation made it possible to achieve bone fusion in post-traumatic disorders of bone regeneration in 95.2 % of cases.Conclusion. With delayed consolidation and developing hypertrophic pseudoarthrosis in conditions of stable fixation with anatomical reposition of fragments, puncture autotransplantation of a mixture of bone marrow with a solution of interferon-beta is proposed. |
| Databáze: | Directory of Open Access Journals |
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