An immune checkpoint score system for prognostic evaluation and adjuvant chemotherapy selection in gastric cancer

Autor: Jia-Bin Wang, Ping Li, Xiao-Long Liu, Qiao-Ling Zheng, Yu-Bin Ma, Ya-Jun Zhao, Jian-Wei Xie, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Li-Chao Liu, Ning-Zi Lian, Ying-Hong Yang, Chang-Ming Huang, Chao-Hui Zheng
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-20260-7
Popis: Expression patterns of immune checkpoints in patients with gastric cancer remain poorly characterized. Here the authors propose an immune scoring system based on the expression of six immunosuppressive ligands to improve the prognostic accuracy in gastric cancer patients and drive the selection of candidates for adjuvant chemotherapy.
Databáze: Directory of Open Access Journals