| Autor: |
N. I. Baranova, N. A. Shkurova, A. V. Fedin |
| Jazyk: |
English<br />Russian |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Известия высших учебных заведений. Поволжский регион: Медицинские науки, Iss 2 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2072-3032 |
| DOI: |
10.21685/2072-3032-2020-2-1 |
| Popis: |
Background. The main purpose of this work is to study features of the microbial picture, the activity of the phagocytosis system and the profile of key cytokines in patients with rhinosinusites and otitis media caused by the type 2 diabetes. Materials and methods. 110 patients were examined. 76 patients had rhinosinusitis and otitis media followed by type 2 diabetes (group 1) and 34 patients had only rhinosinusitis and otitis media (group 2). Results. In microbiological study Staphylococcus epidermidis (23.6 %), Staphylococcus aureus (19,7 %), Pseudomonas aeruginosa (9,2 %) were the most pathogen in patients group 1. The decreases of PCC-test, the decrease of IL-1 level, the increase of IL-10 were identified in patients group 1 in comparison with patients group 2. Conclusions. The decrease of functional indicators according to PCC-test in patients group 1 compared with patients group 2 demonstrates “the lack of reserve of neutrophils activation”. The increase IL-10 proves the activation of regulatory T-cells. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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