Dietary inflammatory index is associated with metabolic dysfunction-associated fatty liver disease among United States adults

Autor: Jing Yan, Jun Zhou, Yuanyuan Ding, Chuantao Tu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Nutrition, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2296-861X
DOI: 10.3389/fnut.2024.1340453
Popis: BackgroundMetabolic dysfunction-associated fatty liver disease (MAFLD) is presently the most prevalent chronic liver disorder globally that is closely linked to obesity, dyslipidemia metabolic syndrome, and type 2 diabetes mellitus (T2DM). Its pathogenesis is strongly associated with inflammation, and diet is a major factor in reducing inflammation. However, current research has focused primarily on exploring the relationship between diet and NAFLD, with less research on its link to MAFLD.MethodsIn this research, using dietary inflammatory index (DII) as a measure to assess dietary quality, we analyzed the relationship between diet and MAFLD. Data from the National Health and Nutrition Examination Survey (NHANES) 2017–2018, including 3,633 adults with complete DII and MAFLD, were used to develop cross-sectional analyses. Logistic regression analysis was adapted for investigating the relationship between DII and MAFLD development. Additionally, subgroup analysis and threshold effect analysis were carried out.ResultsA positive link between DII and MAFLD was found in the fully adjusted model (OR = 1.05; 95%CI, 1.00–1.11, p
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