Clubbed Fingers and Hypertrophic Osteoarthropathy in a Patient with Squamous Cell Carcinoma of the Lung

Autor: Wen-Chi Yang, Shih-Chang Lin, Chung-Jen Chen, Jeng-Hsien Yen, Tsan-Teng Ou, Hong-Wen Liu, Wen-Chan Tsai
Jazyk: angličtina
Rok vydání: 2003
Předmět:
Zdroj: Kaohsiung Journal of Medical Sciences, Vol 19, Iss 4, Pp 183-186 (2003)
Druh dokumentu: article
ISSN: 1607-551X
DOI: 10.1016/S1607-551X(09)70469-3
Popis: Hypertrophic osteoarthropathy (HOA) is characterized by clubbed fingers and periosteal new bone formation. Etiologically, it can be divided into primary and secondary HOA, but its pathogenesis is uncertain. We report a 42-year-old male patient who suffered from painful clubbing fingers and toes. Serial examinations revealed periosteal new bone formation in the four limb long bones and a solid mass lesion in the right upper lung field. Pathologic examination of the resected mass lesion showed squamous cell carcinoma. After surgery and chemotherapy, the severity of clubbed fingers decreased and joint pain improved. Follow-up bone scan also suggested regression of the uptake of radioactivity in the four limb bones. We concluded that the HOA in this case was probably caused by lung cancer.
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