| Autor: |
Taiki Nakajima, Akihiro Nakahata, Naoki Yamada, Keiko Yoshizawa, Tomoaki M. Kato, Mio Iwasaki, Chengzhu Zhao, Hiroshi Kuroki, Makoto Ikeya |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-021-25328-6 |
| Popis: |
Tendon self-renewal occurs rarely and reconstructive surgery comes with significant limitations. Here the authors present an induced pluripotent stem cell-based method to generate tenocytes, analyze their developmental trajectory using scRNA-seq, and demonstrate their contribution to motor function recovery after Achilles tendon injury via engraftment and paracrine effects. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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